FTL Antibody / Ferritin light chain | V7412-20UG

FTL Antibody / Ferritin light chain | V7412-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: FTL/1387

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This FTL antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Immunogen: Amino acids 38-165 from the human protein were used as the immunogen for this FTL antibody.

Storage: Store the FTL antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).