Frataxin Antibody / FXN | V3992-20UG

Frataxin Antibody / FXN | V3992-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: FXN/2124

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This FXN antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Immunogen: Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.

Storage: Store the FXN antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).