Description
FOXM1 Antibody | R31607 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This FOXM1 antibody is available for research use only.
Purity: Antigen affinity
Description: Forkhead box protein M1 is encoded by the FOXM1 gene. It is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. The gene is now known as a human proto-oncogene. Abnormal upregulation of the protein is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It is hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. Additionally, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of the protein brain washes normal cells to adopt cancer-like epigenome.
Immunogen: Human partial recombinant protein (AA 411-763) was used as the immunogen for this FOXM1 antibody.
Storage: After reconstitution, the FOXM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
