FNIP2 Polyclonal Antibody | E-AB-19877

FNIP2 Polyclonal Antibody | E-AB-19877 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Rabbit

Isotype: IgG

Application: WB, ELISA

Research Area: Cancer, Metabolism, Signal transduction

Background: This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin.

Lead Time: 7~10 days

Concentration: 1.14 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human FNIP2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: 122 kDa

Observed Molecular Weight: Refer to figures

Clonality: Polyclonal