Description
Fluorogenic HDAC Substrate 2 (Green fluorescence) | 50038 | Gentaur US, UK & Europe Disrtribition
Category: Deacetylase/Substrates
Application: Study enzyme kinetics, and screen small molecule HDAC inhibitors for drug discovery and HTS applications.
Background: N/A
Description: A fluorogenic, acetylated peptide substrate for HDACs. It is a suitable substrate for class I HDACs (HDACs 1, 2, and 3) and class 2b HDACs (HDACs 6 and 10). This substrate exhibits longer excitation and emission wavelengths (excitation 485 nm, emission 528 nm) than our regular class 1/2b HDAC substrate, #50037, which fluoresces at excitation 350-380 nm, emission at 440-460 nm. This substrate should be used when the inhibitor fluoresces near 450 nm. If autofluorescence is not an issue, we recommend HDAC substrate 3, #50037. For autofluorescent samples using HDACs 4, 5, 7, 8, 9, and 11, we recommend substrate #50042.
Product Type: Substrate
Shippement Condition: -20°C or -80°C
