Description
Fluorescent Human SSTR2 Full Length Protein (VLP) | SS2-HF2G3-20ug| Gentaur Distribution US, UK & Europe
Somatostatin is a peptide with a potent and broad antisecretory action, which makes it an invaluable drug target for the pharmacological management of pituitary adenomas and neuroendocrine tumors. Somatostatin receptors (SSTR1, 2A and B, 3, 4 and 5) belong to the G protein coupled receptor family and have a wide expression pattern in both normal tissues and solid tumors. Investigating the function of each SSTR in several tumor types has provided a wealth of information about the common but also distinct signaling cascades that suppress tumor cell proliferation, survival and angiogenesis. This provided the rationale for developing multireceptor-targeted somatostatin analogs and combination therapies with signaling-targeted agents such as inhibitors of the mammalian (or mechanistic) target of rapamycin (mTOR). The ability of SSTR to internalize and the development of rabiolabeled somatostatin analogs have improved the diagnosis and treatment of neuroendocrine tumors.
Source: Fluorescent Human SSTR2 Full Length Protein (VLP) (SS2-HF2G3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ile 369 (Accession # P30874-1).
Format: Liquid.
Tag: GFP Tag.
Expression System: HEK293.
Expression Region: Met 1 - Ile 369.
Conjugate: GFP Fusion.
Molecular Weight: N/A.
Characteristics: This protein carries a GFP tag.
Purity: N/A.
Buffer: PBS, Arginine, pH7.4.
Storage Conditions: -70℃, aviod light.
Shipping Conditions: Dry ice
