Description
FKBP12 Antibody / FKBP1A | F54946-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, WB, IHC-P
Buffer: N/A
Limitation: This FKBP1A antibody is available for research use only.
Purity: Purified
Description: FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Immunogen: A portion of amino acids 55-83 from the human protein was used as the immunogen for the FKBP1A antibody.
Storage: Aliquot the FKBP1A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
