Description
FITC-Labeled Human CD30 / TNFRSF8 Protein, Fc Tag | CD0-HF250-25ug| Gentaur Distribution US, UK & Europe
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Source: FITC-Labeled Human CD30, His Tag (Cat. No. CD0-HF250) is expressed from human HEK293 cells. It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2). It is the FITC labeled form of Human CD30, His Tag (Cat. No.CD0-H5250).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Phe 19 - Lys 379.
Conjugate: FITC Labeled.
Molecular Weight: 64.6 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.6 kDa. The protein migrates as 70-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃, aviod light.
Shipping Conditions: RT
