Firefly Luciferase THP-1 Cell Line | 78409

Firefly Luciferase THP-1 Cell Line | 78409 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: Use as an internal control in CAR-T co-culture killing assays In vitro and in vivo bioluminescence imaging

Background: THP-1 is a human monocytic leukemia cell line, derived from the peripheral blood of a patient with acute monocytic leukemia. THP-1 cells have Fc and C3b receptors and lack surface and cytoplasmic immunoglobulins. The THP-1 cell line provides a valuable model for studying the mechanisms involved in macrophage differentiation and exploring the regulation of macrophage-specific genes. The signal generated by the firefly luciferase is proportional to cell numbers.

Description: Recombinant THP-1 cells constitutively expressing the firefly (Photinus pyralis) luciferase gene under the control of a CMV promoter.

Product Type: Cell Line

Shippement Condition: -80°C