Firefly Luciferase K562 Cell Line | 78621

Firefly Luciferase K562 Cell Line | 78621 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: 1. In vitro and in vivo Bioluminescence Imaging
2. Use as a negative control in CAR-T or NK co-culture killing assays

Background: The K562 cell line was established from a patient with chronic myelogenous leukemia (CML) in terminal blast crisis. The Firefly Luciferase K562 Cell Line does not express antigens CD19, CD20 or CD22, therefore it makes an excellent negative control in assays that measure specific killing by CAR-T cells targeting B cell antigens CD19, CD20, and CD22. It can also be used as a highly sensitive in vitro target for the natural killer assay.  The signal generated by the firefly luciferase reporter is proportional to cell numbers.

Description: Recombinant K562 cells constitutively expressing firefly (Photinus pyralis) luciferase under the control of a CMV promoter.

Product Type: Cell Line

Shippement Condition: -80°C