Description
Filamin A Antibody / FLNA | F54947-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, IF, IHC-P, WB
Buffer: N/A
Limitation: This Filamin A antibody is available for research use only.
Purity: Antigen affinity purified
Description: Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
Immunogen: A portion of amino acids 1025-1054 from the human protein was used as the immunogen for the Filamin A antibody.
Storage: Aliquot the Filamin A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.