Description
Ficolin 3 Antibody / FCN3 | F54652-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, IHC-P, WB
Buffer: N/A
Limitation: This Ficolin 3 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.
Immunogen: A portion of amino acids 214-243 from the human protein was used as the immunogen for the Ficolin 3 antibody.
Storage: Aliquot the Ficolin 3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
