Description
FGR, GST-tag | 40422 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Cytoplasmic Tyrosine
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: FGR is a protooncogene that is a unique member of the tyrosine kinase gene family. Certain lymphomas (but not sarcomas or carcinomas) express FGR-related messenger RNA. This transcript is detected in Burkitt's lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt's lymphoma cells (1). FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-fgr mRNA per cell (2).
Description: Recombinant full-length human FGR was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_005248.
Product Type: Protein
Shippement Condition: -80°C
