Description
FGR Antibody / c-FGR proto oncogene | F54446-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IF, IHC-P, WB
Buffer: N/A
Limitation: This FGR antibody is available for research use only.
Purity: SAS precipitation
Description: FGR is a member of the Src family of protein tyrosine kinases (PTKs). This protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
Immunogen: A portion of amino acids 3-33 from the human protein was used as the immunogen for the FGR antibody.
Storage: Aliquot the FGR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
