FGG Polyclonal Antibody | E-AB-40412

FGG Polyclonal Antibody | E-AB-40412 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cardiovascular

Background: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Mouse Fibrinogen gamma chain protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification: Antigen Affinity Purification

Dilution: WB 1:1000-1:3000 IHC 1:100-1:300

Conjugation: Unconjugated

Calculated Molecular Weight: 49 kDa

Observed Molecular Weight: 49 kDa

Clonality: Polyclonal