FGG Antibody / Fibrinogen gamma chain / FIBG | F54860-0.08ML

FGG Antibody / Fibrinogen gamma chain / FIBG | F54860-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC-P, IF, WB

Buffer: N/A

Limitation: This FGG antibody is available for research use only.

Purity: Purified

Description: FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.

Immunogen: A portion of amino acids 420-449 from the human protein was used as the immunogen for the FGG antibody.

Storage: Aliquot the FGG antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.