Description
FGFR3 Antibody / Fibroblast Growth Factor Receptor 3 | RQ6767 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, FACS
Buffer: Lyophilized from 1X PBS with 2% Trehalose
Limitation: This Fibroblast Growth Factor Receptor 3 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Fibroblast growth factor receptor 3, also known as CD333, is a protein that in humans is encoded by the FGFR3 gene. This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. The FGFR3 gene is mapped to the HD region on chromosome 4p16.3. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.
Immunogen: Amino acids EGPTLANVSELELPADPKWELSRARLTLGK from the human protein were used as the immunogen for the Fibroblast Growth Factor Receptor 3 antibody.
Storage: After reconstitution, the Fibroblast Growth Factor Receptor 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.