FCGRT / FcRn (IgG Transporter)(FCGRT/2932), 1mg/mL Antibody | BNUM2932-50

FCGRT / FcRn (IgG Transporter)(FCGRT/2932), 1mg/mL Antibody | BNUM2932-50| Gentaur Distribution US, UK & Europe

Summary.: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: Purified, BSA-free.

Storage Buffer: PBS, no BSA, no azide.

Storage Temperature: 35°C to -5°C .

Application: IHC, FFPE (verified).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.