FCGR2A (CD32A) Knockout Jurkat Cell Line | 78549

FCGR2A (CD32A) Knockout Jurkat Cell Line | 78549 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: Use as a control for characterizing FCGR2A in T cells

Background: FCGR2A (also known as CD32A) encodes a low affinity Fc receptor for immunoglobulin G. FcγRIIa is a cell surface receptor expressed on a variety of immune cells such as macrophages and neutrophils. It is involved in phagocytosis and in the clearing of spent immune complexes from the circulation. A polymorphism in FcγRIIa is associated with increased risks of nephritis and lupus.

Description: The FCGR2A Knockout Jurkat cell line was generated by CRISPR/Cas9 genome editing to remove FCGR2A (CD32A), the gene encoding protein FcγRIIa (Fragment crystallizable gamma receptor II a, also known as FcGRIIa, Fc-gamma-RIIa, and CD32A).

Product Type: Cell Line

Shippement Condition: -80°C