FBXW8 Antibody | F54559-0.08ML

FBXW8 Antibody | F54559-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: FACS, IHC-P, WB

Buffer: N/A

Limitation: This FBXW8 antibody is available for research use only.

Purity: Antigen affinity purified

Description: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen: A portion of amino acids 270-299 from the human protein was used as the immunogen for the FBXW8 antibody.

Storage: Aliquot the FBXW8 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.