Description
FBXO32 Polyclonal Antibody | E-AB-67565 | Gentaur US, UK & Europe Disrtribition
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: N/A
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human FBXO32 (NP_478136.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification: Affinity purification
Dilution: WB 1:1000-1:2000 IHC 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 27 kDa/42 kDa
Observed Molecular Weight: 45 kDa
Clonality: N/A
