Fas Antibody / CD95 | F54056-0.1ML

Fas Antibody / CD95 | F54056-0.1ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 50% Glycerol and 0.03% ProClin 300

Format: Purified

Clone: 8C1-B9-F12

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Rat

Application: WB

Buffer: N/A

Limitation: This Fas antibody is available for research use only.

Purity: Protein G affinity

Description: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [UniProt]

Immunogen: A human recombinant protein was used as the immunogen for this Fas antibody.

Storage: Store the Fas antibody at -20 °C.