Description
FADD Antibody | F54009-0.1ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Format: Purified
Clone: 5E8-A7
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IP
Buffer: N/A
Limitation: This FADD antibody is available for research use only.
Purity: Protein G affinity
Description: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]
Immunogen: A human recombinant protein was used as the immunogen for this FADD antibody.
Storage: Store the FADD antibody at -20 °C.
