EYA3 Polyclonal Antibody | E-AB-66408

EYA3 Polyclonal Antibody | E-AB-66408 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IF

Research Area: Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells

Background: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human EYA3 (NP_001981.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 48 kDa/56 kDa/57 kDa/58 kDa/62 kDa

Observed Molecular Weight: 57 kDa/58 kDa

Clonality: N/A