Description
Exportin 1 Antibody / XPO1 / CRM1 | RQ4719 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: AEFD-24
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This CRM1 antibody is available for research use only.
Purity: Affinity purified
Description: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Immunogen: A synthetic peptide specific to human CRM1 / XPO1 was used as the immunogen for the CRM1 antibody.
Storage: Store the CRM1 antibody at -20 °C.
