Description
EXOC2 Polyclonal Antibody | E-AB-63135 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IF
Research Area: Signal Transduction
Background: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human EXOC2 (NP_060773.3).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification: Affinity purification
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 104 kDa
Observed Molecular Weight: 108 kDa
Clonality: N/A
