Description
EV450 Anti-Mouse IL-17A Antibody | DL22997F-2 | Gentaur US, UK & Europe Disrtribition
Synonyms: Interleukin-17A,Il17a,Ctla8
Reactivity: Mouse
Host: Mouse
Application: ICFCM
Background: The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-49A in vivo.
Concentration: 0.5 mg/mL
Conjugation: EV450
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Mouse IgG1, κ
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
