Description
EV450 Anti-Human/Mouse/Rat CD47 Antibody | DL22838F-3 | Gentaur US, UK & Europe Disrtribition
Synonyms: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Reactivity: Human, Mouse, Rat
Host: Mouse
Application: FCM
Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
Concentration: 0.5 mg/mL
Conjugation: EV450
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Mouse IgG1, κ
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
