Description
Estrogen Receptor beta 2 Antibody | V8668-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: 57/3
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF, WB, IHC-P
Buffer: N/A
Limitation: This Estrogen Receptor beta 2 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: This MAb recognizes the estrogen receptor beta 2 isoform, expressed in cell nuclei of a range of human tissues including ovary, placenta, testis and vas deferens. No cross-reactivity is seen with estrogen receptor beta 1 isoform. This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members.
Immunogen: Amino acids CGMKMETLLPEATMEQ from the C terminus of the human estrogen receptor beta 2 isomer were used as the immunogen for the Estrogen Receptor beta 2 antibody.
Storage: Store the Estrogen Receptor beta 2 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
