Description
Estrogen Receptor Antibody (isoform 4) | F47480-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, ELISA
Buffer: N/A
Limitation: This Estrogen Receptor antibody (isoform 4) is available for research use only.
Purity: Antigen affinity
Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Immunogen: A portion of amino acids 271-300 from the human protein was used as the immunogen for this Estrogen Receptor antibody (isoform 4).
Storage: Aliquot the Estrogen Receptor antibody (isoform 4) and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
