Description
Estrogen Receptor alpha Antibody | V8434-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: ESR1/3565
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This Estrogen Receptor alpha antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
Immunogen: A portion of amino acids 129-312 from the human protein was used as the immunogen for the Estrogen Receptor alpha antibody.
Storage: Store the Estrogen Receptor alpha antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).