Description
ERCC1 Polyclonal Antibody | E-AB-19768 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: WB, ELISA
Research Area: Cancer, Epigenetics and Nuclear Signaling
Background: Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11, XPF and ERCC4, which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1, together with RRM1, are determinants of survival after surgical treatment of early-stage, non-small-cell lung cancer. (Ref: Simon, ER. 2005)
Lead Time: 7~10 days
Concentration: 1.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human ERCC1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 33 kDa
Observed Molecular Weight: Refer to figures
Clonality: Polyclonal
