Equilibrative nucleoside transporter 1 Antibody / ENT1 | F54342-0.4ML

Equilibrative nucleoside transporter 1 Antibody / ENT1 | F54342-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, FACS, IHC-P

Buffer: N/A

Limitation: This ENT1 antibody is available for research use only.

Purity: Antigen affinity purified

Description: ENT1, or Equilibrative nucleoside transporter 1, is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.

Immunogen: A portion of amino acids 402-431 from the human protein was used as the immunogen for the ENT1 antibody.

Storage: Aliquot the ENT1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.