EPHB3, GST-tag | 40186

EPHB3, GST-tag | 40186 | Gentaur US, UK & Europe Disrtribition

Category: Kinase/Receptor Tyrosine

Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Background: EPHB3 is a member of the Ephrin receptor family and is expressed during embryonic development in multiple regions of the central nervous system. In adult brain, EPHB3 is expressed in the cerebellum, raphe pallidus, hippocampus, entorhinal cortex, and both motor and sensory cortices (1). EPHB3 is involved in the maintenance of mature neuronal connections and/or re-arrangement of synaptic connections during late stages of development. EPHB3 plays a role in the regulation of cell adhesion and migration, and the catalytic activity of EPHB3 is required for inhibition of integrin-mediated cell adhesion (2).

Description: Recombinant human EPHB3 (a.a. 585-end), with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.

Product Type: Protein

Shippement Condition: -80°C