EpCAM Antibody / Cytoplasmic domain | V8850-20UG

EpCAM Antibody / Cytoplasmic domain | V8850-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: EGP40/7035R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant EpCAM antibody should be determined by the researcher.

Purity: Protein A affinity

Description: Epithelial cellular adhesion molecule (Ep-CAM), also called epithelial specific antigen (ESA), is a 40-43kDa transmembrane epithelial glycoprotein. It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Immunogen: A portion of amino acids 289-314 of human EpCAM was used as the immunogen for the recombinant EpCAM antibody.

Storage: Aliquot the recombinant EpCAM antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cell surface, cytoplasmic