Description
EIF4A2 Antibody | F54470-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS, IHC-P
Buffer: N/A
Limitation: This EIF4A2 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Eukaryotic initiation factor 4A plays an important role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins. Two highly homologous forms of functional EIF4A genes, Eif4a1 and Eif4a2, have been isolated in mice; yeast cells also possess 2 EIF4A genes, TIF1 and TIF2. The murine Eif4a and yeast TIF genes appear to belong to a DEAD-box gene family, whose members exhibit extensive amino acid similarity and contain the asp-glu-ala-asp (DEAD) sequence. DEAD-box genes have been identified in species ranging from E-coli to humans. Their function appears to be related to transcriptional/translational regulation (referenced from OMIM).
Immunogen: A portion of amino acids 333-360 from the human protein was used as the immunogen for the EIF4A2 antibody.
Storage: Aliquot the EIF4A2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
