Description
EGF Receptor / EGFR Antibody (C-terminal region) | V9263-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: EGFR/4575
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This EGF Receptor antibody is available for research use only.
Purity: Protein A/G affinity
Description: This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Immunogen: A portion of amino acids 1163-1191 from the C-terminal region of human EGFR was used as the immunogen for the EGF Receptor antibody.
Storage: Aliquot the EGF Receptor antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
