Description
EFL1 Antibody / EFTUD1 | F54540-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: IHC-P, FACS, WB
Buffer: N/A
Limitation: This EFL1 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits. [UniProt]
Immunogen: A portion of amino acids 1062-1090 from the human protein was used as the immunogen for the EFL1 antibody.
Storage: Aliquot the EFL1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
