EEF2K, GST-tag | 40057

EEF2K, GST-tag | 40057 | Gentaur US, UK & Europe Disrtribition

Category: Kinase-Serine/Threonine/Protein

Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Background: EEF2K is a highly conserved calmodulin-dependent protein kinase that links activation of cell surface receptors to cell division. EEF2K is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2), an abundant cytoplasmic protein that catalyzes the movement of the ribosome along mRNA during translation in eukaryotic cells, and inhibits the EEF2 function (1). EEF2K is highly expressed in heart and skeletal muscle, suggesting that EEF2 phosphorylation may be particularly important in muscle. EEF2K is highly expressed in patients with systemic lupus erythematosus (2) as well as in many cancers.

Description: Recombinant human eukaryotic elongation factor 2 (EEF2K), full length, with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.

Product Type: Protein

Shippement Condition: -80°C