EDG1 Antibody | N1039-100UG

EDG1 Antibody | N1039-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB

Buffer: 1X PBS, pH 7.4

Limitation: This EDG1 antibody is available for research use only.

Purity: Protein A affinity chromatography

Description: EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.

Immunogen: A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.

Storage: Aliquot the EDG1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.