ECE2 Polyclonal Antibody | E-AB-16986

ECE2 Polyclonal Antibody | E-AB-16986 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IHC, ELISA

Research Area: Cardiovascular, Neuroscience, Signal transduction

Background: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human ECE2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification: Affinity purification

Dilution: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000

Conjugation: Unconjugated

Calculated Molecular Weight: 100 kDa

Observed Molecular Weight: N/A

Clonality: Polyclonal