EBP1 Antibody / ErbB3-binding protein 1 / PA2G4 | F54781-0.4ML

EBP1 Antibody / ErbB3-binding protein 1 / PA2G4 | F54781-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IF, FACS, IHC-P, WB

Buffer: N/A

Limitation: This PA2G4 antibody is available for research use only.

Purity: Purified

Description: PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. The protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. It is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. It has been implicated in growth inhibition and the induction of differentiation of human cancer cells.

Immunogen: A portion of amino acids 228-255 from the human protein was used as the immunogen for the PA2G4 antibody.

Storage: Aliquot the PA2G4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.