E Cadherin Antibody | F44156-0.4ML

E Cadherin Antibody | F44156-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This E Cadherin antibody is available for research use only.

Purity: Purified

Description: CDH1 is a classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization.

Immunogen: A portion of amino acids 160-189 from the human protein was used as the immunogen for this E Cadherin antibody.

Storage: Aliquot the E Cadherin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.