Dystrophin Antibody / DMD | V7555IHC-7ML

Dystrophin Antibody / DMD | V7555IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: DSTN-1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Dystrophin antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: The DMD gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [RefSeq]

Immunogen: Amino acids 114-263 from the human protein were used as the immunogen for the Dystrophin antibody.

Storage: Store the Dystrophin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).