Dystrobrevin alpha Antibody / DTNA | F54653-0.4ML

Dystrobrevin alpha Antibody / DTNA | F54653-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: IF, IHC-P, WB

Buffer: N/A

Limitation: This Dystrobrevin alpha antibody is available for research use only.

Purity: Antigen affinity purified

Description: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Immunogen: A portion of amino acids 692-721 from the human protein was used as the immunogen for the Dystrobrevin alpha antibody.

Storage: Aliquot the Dystrobrevin alpha antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.