DYRK1A Antibody | F50504-0.08ML

DYRK1A Antibody | F50504-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This DYRK1A antibody is available for research use only.

Purity: Purified

Description: DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.

Immunogen: A portion of amino acids 107-136 from the human protein was used as the immunogen for this DYRK1A antibody.

Storage: Aliquot the DYRK1A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.