Description
DSCR1 Antibody | F40133-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This DSCR1 antibody is available for research use only.
Purity: Purified
Description: DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Immunogen: A portion of amino acids 75-104 from the human protein was used as the immunogen for this DSCR1 antibody.
Storage: Aliquot the DSCR1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
