Description
DRP1 Antibody (DNM1L) | F53331-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This DRP1 antibody is available for research use only.
Purity: Antigen affinity
Description: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. [UniProt]
Immunogen: This DRP1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 557-590 amino acids from the C-terminal region of human DRP1/DNM1L.
Storage: Aliquot the DRP1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.