Description
DRD1 Antibody Dopamine Receptor D1 | R30647 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Buffer: N/A
Limitation: This DRD1 antibody is available for research use only.
Purity: Antigen affinity
Description: Dopamine receptor D1 is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2Rs inhibit adenylyl cyclase, but D1Rs stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. DRD1/2 are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1Rs regulate neuron growth and differentiation, influence behaviour and modify DRD2-mediated events. And the presence of a DRD1 gene restriction fragment length polymorphism will be helpful for future disease linkage studies. This protein also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.
Immunogen: Amino acids 221-242 (AQKQIRRIAALERAAVHAKNCQ-human) were used as the immunogen for this DRD1 antibody.
Storage: The DRD1 antibody can be stored at 4oC to -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freeze/thaws.
