Description
DR6 Antibody (Death Receptor 6) | F45509-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This DR6 antibody is available for research use only.
Purity: Antigen affinity
Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Immunogen: A portion of amino acids 356-385 from the human protein was used as the immunogen for this DR6 antibody.
Storage: Aliquot the DR6 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
